Limb-Girdle Muscular Dystrophy 2C

Limb-girdle muscular dystrophy is a term used to describe 19 types of muscular dystrophy, of which LGMD2C is the most severe kind. This page provides details about limb-girdle muscular dystrophy type 2C.


LGMD2C At A Glance

Muscular dystrophy is a group of hereditary muscle diseases and includes the 19 limb-girdle muscular dystrophies, in which the muscles most severely affected are the hip and shoulder muscles, the so-called "limb girdle muscles."

Limb-girdle muscular dystrophy type 2C ("LGMD2C") is the most severe limb-girdle muscular dystrophy and is one of the two or three most severe muscular dystrophies. Children with LGMD2C cannot produce a protein, gamma sarcoglycan, necessary for muscle strength and function. Instead of muscles growing stronger after exercise, muscles deteriorate. Although children with LGMD2C like Kurt and Peter are able to live normally at young ages, over time their deteriorating muscles prevent them from engaging in a number of typical childhood activities. The disease is highly variable. Many children with LGMD2C are in a wheelchair in their mid-to-late teenage years.

Pete

Pete loves to swing- the higher the better.

Kurt

Kurt loves Dim Sum.